Wednesday, March 10, 2010

Wednesday March 10, 2010
Oxygen Index

Oxygen index (OI) is one of the objective number to measure the severity of ARDS/lung disease. Recently it has been postulated as cutoff point for initiation of ECMO (extracorporeal membrane oxygenation). There has been a significant resistant in the use of ECMO due to various other non-conventional methods available like high-frequency oscillatory ventilation (HFOV), inhaled nitric oxide (iNO), prone positioning, APRV ventiliation etc. One study 1 showed that OI of 33.2 is a suitable cutoff value for ECMO. Otherwise also it has been said as a better indicator of lung function than P/F ratio


Oxygen Index (OI) = FiO2 x MAP x 100
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PaO2



* MAP = Mean Airway pressure
FiO2 is in %


1. Oxygenation index for extracorporeal membrane oxygenation: is there predictive significance? - Journal of Artificial Organs, Volume 10, Number 1, March 2007 , pp. 6-9(4)